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| Registros recuperados : 11 | |
| 2. |  | TREVISAN, L.; ATTILIO, D. B.; NINOV, K.; PADUAN, M.; LEDUR, M. C.; COUTINHO, L. L.; ROSÁRIO, M. F. do. Desenho e otimização de primers do gene FGF2 associado ao crescimento da galinha doméstica. In: SIMPÓSIO INTERNACIONAL DE INICIAÇÃO CIENTÍFICA DA UNIVERSIDADE DE SÃO PAULO, 20., 2012, Pirassununga. [Resumos]. São Paulo: USP, 2012. SIICUSP 2012.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 3. | | MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; LEDUR, M. C.; GASPARIN, G.; ANDRADE, S. C. da S.; PADUAN, M.; COUTINHO, L. L. Identification of mutations in a QTL region on chromosome 3 associated with fatness in chickens. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Programme and abstract book... [S.l.: s.n.], 2013. p. 38. ISAFG 2013. AB.31| Biblioteca(s): Embrapa Suínos e Aves. |
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| 4. | | GODOY, T. F.; MOREIRA, G. C. M.; BOSCHIERO, C.; LEDUR, M. C.; GASPARIN, G.; ANDRADE, S. C. da S.; PADUAN, M.; COUTINHO, L. L. Identification of polymorphisms in a QTL region on chicken chromosome 2 associated with muscle deposition. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Programme and abstract book... [S.l.: s.n.], 2013. p. 39. ISAFG 2013.AB.32| Biblioteca(s): Embrapa Suínos e Aves. |
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| 5. | | BOSCHIERO, C.; MOREIRA, G. C. M.; GHEYAS, A.; GODOY, T. F.; GASPARIN, G.; MARIANI, P. D. S. C.; PADUAN, M.; CESAR, A. S. M.; LEDUR, M. C.; COUTINHO, L. L. Genome-wide characterization of genetic variants and putative regions under selection in meat and egg-type chicken lines. BMC Genomics, v. 19, n. 83, 2018.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 6. | | MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. Discovery of SNPs potentially associated with fatness in a QTL region on chicken chromosome 3. In: WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver. Proceedings... Vancouver: WCGALP: American Society of Animal Science, 2014.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 7. | | DEFANT, H.; MEIRA, A. N.; COUTINHO, L. L.; REGITANO, L. C. de A.; POLETI, M. D.; MOREIRA, G. C. M.; PADUAN, M.; MARIANI, P.; ZERLOTINI NETO, A.; MOURÃO, G. B.; CESAR, A. S. M. Novel polymorphisms in the PLIN2 gene of Nellore cattle. Genetics and Molecular Research, v. 18, n. 3, 2019. Não paginado. Na publicação: Luciana CA Regitano, Adhemar Zerlotini. gmr16039963.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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| 8. | | BOSCHIERO, C.; GODOY, T. F.; MOREIRA, G. C. M.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. SNP discovery in a QTL region associated with breast muscle deposition on chicken chromosome 2. In: WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver. Proceedings... Vancouver: WCGALP: American Society of Animal Science, 2014.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 9. | | GODOY, T. F.; MOREIRA, G. C. M.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. SNP and INDEL detection in a QTL region on chicken chromosome 2 associated with muscle deposition. Animal Genetics, v. 6, n. 2, p. 158-163, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 10. | | BOSCHIERO, C.; GHEYAS, A.; GODOY, T. F.; MOREIRA, G. C. M.; GRADE, C. V. C.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. da S.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. SNPs and INDELS detection in the chicken myostation gene and its intergenic regions. In: INTERNATIONAL SYMPOSIUM ON ANIMAL FUNCTIONAL GENOMICS, 5., 2013, Guarujá. Programme and abstract book... [S.l.: s.n.], 2013. p. 24. ISAFG 2013. AB.17.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 11. | | MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; ANDRADE, S. C. S.; PADUAN, M.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. Variant discovery in a QTL region on chromosome 3 associated with fatness in chickens. Animal Genetic, v. 46, n. 2, p. 141-147, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| Registros recuperados : 11 | |
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Registro Completo
|
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
|
Data corrente: |
23/01/2020 |
|
Data da última atualização: |
20/04/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
DEFANT, H.; MEIRA, A. N.; COUTINHO, L. L.; REGITANO, L. C. de A.; POLETI, M. D.; MOREIRA, G. C. M.; PADUAN, M.; MARIANI, P.; ZERLOTINI NETO, A.; MOURÃO, G. B.; CESAR, A. S. M. |
|
Afiliação: |
HELOISA DEFANT, Esalq/USP; ARIANA N. MEIRA, Esalq/USP; LUIZ L. COUTINHO, Esalq/USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; MIRELE D. POLETI, USP; GABRIEL C. M. MOREIRA, Esalq/USP; MARCELA PADUAN, Esalq/USP; PILAR MARIANI, Esalq/USP; ADHEMAR ZERLOTINI NETO, CNPTIA; GERSON B. MOURÃO, Esalq/USP; ALINE S. M. CESAR, Esalq/USP. |
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Título: |
Novel polymorphisms in the PLIN2 gene of Nellore cattle. |
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Ano de publicação: |
2019 |
|
Fonte/Imprenta: |
Genetics and Molecular Research, v. 18, n. 3, 2019. |
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Páginas: |
Não paginado. |
|
Idioma: |
Inglês |
|
Notas: |
Na publicação: Luciana CA Regitano, Adhemar Zerlotini. gmr16039963. |
|
Conteúdo: |
ABSTRACT. Genetic variations in genes involved in lipid storage, which also may interfere with important phenotypic traits such as intramuscular fat deposition in cattle, can represent useful markers in marker assisted selection programs. An important candidate gene is perilipin 2 (PLIN2) that plays a role in the capture of long chain fatty acids and in the formation and stabilization of lipid droplets in different tissues including muscle. As reported by our group, PLIN2 expression level was associated with trans-eQTL (expression quantitative loci distant of gene associated) at chr3: 87, 253, 086 in Nellore cattle, where animals with different genotypes showed different expression level of PLIN2 among the 193 animals and the co-expression analysis detected correlation with intramuscular fat, palmitoleic, oleic and linoleic acids. Then, the objective of this study was to identify and characterize polymorphisms present in the PLIN2 gene of Nellore cattle. To date, there is not much information on mutations in the PLIN2 gene in Bos indicus animals. A total of 134 single nucleotide polymorphisms (SNPs) were identified in the genomic region of PLIN2 gene and five of those are novel with a moderate impact. These SNPs may change the protein effectiveness and, after further association studies and functional validation, could be used as genomic markers in animal breeding program. |
|
Palavras-Chave: |
Biological process; Expressão gênica; Gordura intramuscular; Gota lipídica; Lipid droplet; Perilipin 2; PLIN2; Polimorfismo de nucleotídeo único; Processos biológicos; SNP; Variants. |
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Thesagro: |
Bos Indicus; Gado. |
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Thesaurus NAL: |
Cattle; Gene expression; Intramuscular fat; Nellore; Single nucleotide polymorphism. |
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Categoria do assunto: |
--
G Melhoramento Genético |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/209752/1/NovelPolymorphismsPLIN2.pdf
|
|
Marc: |
LEADER 02742naa a2200481 a 4500
001 2119464
005 2020-04-20
008 2019 bl uuuu u00u1 u #d
100 1 $aDEFANT, H.
245 $aNovel polymorphisms in the PLIN2 gene of Nellore cattle.$h[electronic resource]
260 $c2019
300 $aNão paginado.
500 $aNa publicação: Luciana CA Regitano, Adhemar Zerlotini. gmr16039963.
520 $aABSTRACT. Genetic variations in genes involved in lipid storage, which also may interfere with important phenotypic traits such as intramuscular fat deposition in cattle, can represent useful markers in marker assisted selection programs. An important candidate gene is perilipin 2 (PLIN2) that plays a role in the capture of long chain fatty acids and in the formation and stabilization of lipid droplets in different tissues including muscle. As reported by our group, PLIN2 expression level was associated with trans-eQTL (expression quantitative loci distant of gene associated) at chr3: 87, 253, 086 in Nellore cattle, where animals with different genotypes showed different expression level of PLIN2 among the 193 animals and the co-expression analysis detected correlation with intramuscular fat, palmitoleic, oleic and linoleic acids. Then, the objective of this study was to identify and characterize polymorphisms present in the PLIN2 gene of Nellore cattle. To date, there is not much information on mutations in the PLIN2 gene in Bos indicus animals. A total of 134 single nucleotide polymorphisms (SNPs) were identified in the genomic region of PLIN2 gene and five of those are novel with a moderate impact. These SNPs may change the protein effectiveness and, after further association studies and functional validation, could be used as genomic markers in animal breeding program.
650 $aCattle
650 $aGene expression
650 $aIntramuscular fat
650 $aNellore
650 $aSingle nucleotide polymorphism
650 $aBos Indicus
650 $aGado
653 $aBiological process
653 $aExpressão gênica
653 $aGordura intramuscular
653 $aGota lipídica
653 $aLipid droplet
653 $aPerilipin 2
653 $aPLIN2
653 $aPolimorfismo de nucleotídeo único
653 $aProcessos biológicos
653 $aSNP
653 $aVariants
700 1 $aMEIRA, A. N.
700 1 $aCOUTINHO, L. L.
700 1 $aREGITANO, L. C. de A.
700 1 $aPOLETI, M. D.
700 1 $aMOREIRA, G. C. M.
700 1 $aPADUAN, M.
700 1 $aMARIANI, P.
700 1 $aZERLOTINI NETO, A.
700 1 $aMOURÃO, G. B.
700 1 $aCESAR, A. S. M.
773 $tGenetics and Molecular Research$gv. 18, n. 3, 2019.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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